Session 46: Endometrial Function During Implantation Window

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چکیده

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منابع مشابه

Endometrial MicroRNA Signature during the Window of Implantation Changed in Patients with Repeated Implantation Failure

BACKGROUND At present, a diagnostic tool with high specificity for impaired endometrial receptivity, which may lead to implantation failure, remains to be developed. We aimed to assess the different endometrial microRNA (miRNA) signatures for impaired endometrial receptivity by microarray analysis. METHODS A total of 12 repeated implantation failure (RIF) patients and 10 infertile patients, w...

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Ultrastructural Modifications of Human Endometrium during the Window of Implantation

The endometrium is a highly dynamic tissue empowered with the capacity to undergo cyclic dramatic changes in response to ovarian steroid hormones, ultimately aiming to create a window of receptivity for blastocyst implantation. Intensive research has been performed to understand and establish morphological and molecular correlates of embryo implantation. However, it still remains a biological m...

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Overexpression of Endometrial Estrogen Receptor-Alpha in The Window of Implantation in Women with Unexplained Infertility

Objective Background: Failure in the endometrial receptivity may account for a significant number of infertility cases including unexplained infertility in women. Reduction in the endometrial estrogen receptor-alpha (ER-α) expression during window of implantation may be a critical event that coincides with expression of specific genes and providing a receptive endometrium. The aim of present st...

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Effect of Myomectomy on Endometrial Glutathione Peroxidase 3 (GPx3) and Glycodelin mRNA Expression at the Time of the Implantation Window

Background: In fertile women, glycodelin and glutathione peroxidase 3 (GPx3) genes expression rises during the luteal phase, with a peak occurring during the implantation window. The expression of these genes decreases in women with myomas. To determine whether myomectomy would reverse glycodelin and GPx3 expression, we evaluated the transcript levels of these genes in the endometrium of patien...

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Uterine ALK3 is essential during the window of implantation.

The window of implantation is defined by the inhibition of uterine epithelial proliferation, structural epithelial cell remodeling, and attenuated estrogen (E2) response. These changes occur via paracrine signaling between the uterine epithelium and stroma. Because implantation defects are a major cause of infertility in women, identifying these signaling pathways will improve infertility inter...

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ژورنال

عنوان ژورنال: Human Reproduction

سال: 2010

ISSN: 0268-1161,1460-2350

DOI: 10.1093/humrep/de.25.s1.46